Bioprinting holds the promise to generate functional tissuesthrough computer-aided transfer processes that allow the patterning and assembly of living and non-living materials. In the most common strategy, cells are combined with hydrogel precursors and eventually biologically active molecules to generate bioink formulations that allow the printing of complex cellularized constructs for tissue engineering and regenerative medicine applications. Although hydrogels have been used in biomedical field for several decades, the design of hydrogels for bioprinting represents a major challenge as they need to exhibit appropriate printability and tunable biophysical properties, while simultaneously providing a suitable microenvironment where entrapped cells can migrate, proliferate and synthetize new extracellular matrix. The design of bioinks with controllable properties that closely mimic the cell microenvironment represents an intense topic of research in the field. This talk will provide a brief overview of the evolution of bioprinting, focusing on the design and bioprinting of biomimetic polymer-peptide hydrogel bioinks for skin tissue engineering